Principal Scientist jobs in the USA

39 open Principal Scientist jobs in the USA right now, 22 of them posted in the last 30 days, at 13 companies. Numbers from the job boards and company careers pages GoJob.now reads, updated November 2026.

39open jobs
154,000 USD median posted pay a year
31%of ads show pay
10%remote

Pay

Half of the 12 ads that posted pay offer between 138,000 USD and 176,000 USD a year (the middle of each posted range, as the ad states it: gross pay for employment, before VAT for B2B). The median is 154,000 USD.

31% of the open ads show pay at all. Ads without pay are counted in the totals, not in the range.

How the jobs are set up

Companies hiring most

  1. Johnson & Johnson 10 open
  2. AbbVie 7 open
  3. Flagship Pioneering, Inc. 5 open
  4. Praxis Precision Medicines, Inc. 3 open
  5. Xaira Therapeutics 3 open
  6. Precision Medicine Group 2 open
  7. Precisionmedicinegroup 2 open
  8. Precision for Medicine 2 open
  9. Sonova Group 1 open
  10. Iambic Therapeutics, Inc 1 open

Skills the ads ask for

People managementMachine learningEnglishArchitectureAI agentsPythonStatisticsLLMsGenerative AIRoadmapsDeep learningPyTorch

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